TY - JOUR AU - Roberts, P. J. AU - Der, C. J. PY - 2007 DA - 2007// TI - Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210422 DO - 10.1038/sj.onc.1210422 ID - Roberts2007 ER - TY - JOUR AU - Kole, H. K. AU - Resnick, R. J. AU - Van Doren, M. AU - Racker, E. PY - 1991 DA - 1991// TI - Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts JO - Arch Biochem Biophys VL - 286 UR - https://doi.org/10.1016/0003-9861(91)90084-V DO - 10.1016/0003-9861(91)90084-V ID - Kole1991 ER - TY - JOUR AU - Racker, E. AU - Resnick, R. J. AU - Feldman, R. PY - 1985 DA - 1985// TI - Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes JO - Proc Natl Acad Sci U S A VL - 82 UR - https://doi.org/10.1073/pnas.82.11.3535 DO - 10.1073/pnas.82.11.3535 ID - Racker1985 ER - TY - JOUR AU - Ramanathan, A. AU - Wang, C. AU - Schreiber, S. L. PY - 2005 DA - 2005// TI - Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements JO - Proc Natl Acad Sci U S A VL - 102 UR - https://doi.org/10.1073/pnas.0502267102 DO - 10.1073/pnas.0502267102 ID - Ramanathan2005 ER - TY - JOUR AU - Telang, S. AU - Lane, A. N. AU - Nelson, K. K. AU - Arumugam, S. AU - Chesney, J. PY - 2007 DA - 2007// TI - The oncoprotein H-RasV12 increases mitochondrial metabolism JO - Mol Cancer VL - 6 UR - https://doi.org/10.1186/1476-4598-6-77 DO - 10.1186/1476-4598-6-77 ID - Telang2007 ER - TY - CHAP AU - Chesney, J. AU - Telang, S. PY - 2012 DA - 2012// TI - Regulation of Glycolytic and Mitochondrial Metabolism by Ras BT - Curr Pharm Biotechnol ID - Chesney2012 ER - TY - JOUR AU - Weinberg, F. AU - Hamanaka, R. AU - Wheaton, W. W. AU - Weinberg, S. AU - Joseph, J. AU - Lopez, M. AU - Kalyanaraman, B. AU - Mutlu, G. M. AU - Budinger, G. R. AU - Chandel, N. S. PY - 2010 DA - 2010// TI - Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1003428107 DO - 10.1073/pnas.1003428107 ID - Weinberg2010 ER - TY - JOUR AU - Fan, T. W. AU - Lane, A. N. AU - Higashi, R. M. AU - Farag, M. A. AU - Gao, H. AU - Bousamra, M. AU - Miller, D. M. PY - 2009 DA - 2009// TI - Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM) JO - Mol Cancer VL - 8 UR - https://doi.org/10.1186/1476-4598-8-41 DO - 10.1186/1476-4598-8-41 ID - Fan2009 ER - TY - JOUR AU - Minamoto, T. AU - Mai, M. AU - Ronai, Z. PY - 2000 DA - 2000// TI - K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers–a review JO - Cancer Detect Prev VL - 24 ID - Minamoto2000 ER - TY - JOUR AU - Dong, L. F. AU - Freeman, R. AU - Liu, J. AU - Zobalova, R. AU - Marin-Hernandez, A. AU - Stantic, M. AU - Rohlena, J. AU - Valis, K. AU - Rodriguez-Enriquez, S. AU - Butcher, B. PY - 2009 DA - 2009// TI - Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-08-2439 DO - 10.1158/1078-0432.CCR-08-2439 ID - Dong2009 ER - TY - JOUR AU - Ralph, S. J. AU - Rodriguez-Enriquez, S. AU - Neuzil, J. AU - Moreno-Sanchez, R. PY - 2010 DA - 2010// TI - Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger JO - Mol Aspects Med VL - 31 UR - https://doi.org/10.1016/j.mam.2009.12.006 DO - 10.1016/j.mam.2009.12.006 ID - Ralph2010 ER - TY - JOUR AU - Gibson, B. W. PY - 2005 DA - 2005// TI - The human mitochondrial proteome: oxidative stress, protein modifications and oxidative phosphorylation JO - Int J Biochem Cell Biol VL - 37 UR - https://doi.org/10.1016/j.biocel.2004.11.013 DO - 10.1016/j.biocel.2004.11.013 ID - Gibson2005 ER - TY - JOUR AU - Kadenbach, B. AU - Huttemann, M. AU - Arnold, S. AU - Lee, I. AU - Bender, E. PY - 2000 DA - 2000// TI - Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase JO - Free Radic Biol Med VL - 29 UR - https://doi.org/10.1016/S0891-5849(00)00305-1 DO - 10.1016/S0891-5849(00)00305-1 ID - Kadenbach2000 ER - TY - JOUR AU - Kadenbach, B. AU - Merle, P. PY - 1981 DA - 1981// TI - On the function of multiple subunits of cytochrome c oxidase from higher eukaryotes JO - FEBS Lett VL - 135 UR - https://doi.org/10.1016/0014-5793(81)80932-5 DO - 10.1016/0014-5793(81)80932-5 ID - Kadenbach1981 ER - TY - JOUR AU - Brookes, P. S. AU - Levonen, A. L. AU - Shiva, S. AU - Sarti, P. AU - Darley-Usmar, V. M. PY - 2002 DA - 2002// TI - Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species JO - Free Radic Biol Med VL - 33 UR - https://doi.org/10.1016/S0891-5849(02)00901-2 DO - 10.1016/S0891-5849(02)00901-2 ID - Brookes2002 ER - TY - JOUR AU - Capaldi, R. A. PY - 1990 DA - 1990// TI - Structure and function of cytochrome c oxidase JO - Annu Rev Biochem VL - 59 UR - https://doi.org/10.1146/annurev.bi.59.070190.003033 DO - 10.1146/annurev.bi.59.070190.003033 ID - Capaldi1990 ER - TY - JOUR AU - Kadenbach, B. AU - Jarausch, J. AU - Hartmann, R. AU - Merle, P. PY - 1983 DA - 1983// TI - Separation of mammalian cytochrome c oxidase into 13 polypeptides by a sodium dodecyl sulfate-gel electrophoretic procedure JO - Anal Biochem VL - 129 UR - https://doi.org/10.1016/0003-2697(83)90586-9 DO - 10.1016/0003-2697(83)90586-9 ID - Kadenbach1983 ER - TY - JOUR AU - Anderson, W. F. AU - Ohlendorf, D. H. AU - Takeda, Y. AU - Matthews, B. W. PY - 1981 DA - 1981// TI - Structure of the cro repressor from bacteriophage lambda and its interaction with DNA JO - Nature VL - 290 UR - https://doi.org/10.1038/290754a0 DO - 10.1038/290754a0 ID - Anderson1981 ER - TY - JOUR AU - Capaldi, R. A. AU - Marusich, M. F. AU - Taanman, J. W. PY - 1995 DA - 1995// TI - Mammalian cytochrome-c oxidase: characterization of enzyme and immunological detection of subunits in tissue extracts and whole cells JO - Methods Enzymol VL - 260 UR - https://doi.org/10.1016/0076-6879(95)60134-1 DO - 10.1016/0076-6879(95)60134-1 ID - Capaldi1995 ER - TY - JOUR AU - Campian, J. L. AU - Gao, X. AU - Qian, M. AU - Eaton, J. W. PY - 2007 DA - 2007// TI - Cytochrome C oxidase activity and oxygen tolerance JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M604547200 DO - 10.1074/jbc.M604547200 ID - Campian2007 ER - TY - JOUR AU - Herrmann, P. C. AU - Gillespie, J. W. AU - Charboneau, L. AU - Bichsel, V. E. AU - Paweletz, C. P. AU - Calvert, V. S. AU - Kohn, E. C. AU - Emmert-Buck, M. R. AU - Liotta, L. A. AU - Petricoin, E. F. PY - 2003 DA - 2003// TI - Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer JO - Proteomics VL - 3 UR - https://doi.org/10.1002/pmic.200300461 DO - 10.1002/pmic.200300461 ID - Herrmann2003 ER - TY - JOUR AU - Soejima, K. AU - Fang, W. AU - Rollins, B. J. PY - 2003 DA - 2003// TI - DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras JO - Oncogene VL - 22 UR - https://doi.org/10.1038/sj.onc.1206510 DO - 10.1038/sj.onc.1206510 ID - Soejima2003 ER - TY - JOUR AU - Srivastava, S. K. AU - Yuasa, Y. AU - Reynolds, S. H. AU - Aaronson, S. A. PY - 1985 DA - 1985// TI - Effects of two major activating lesions on the structure and conformation of human ras oncogene products JO - Proc Natl Acad Sci U S A VL - 82 UR - https://doi.org/10.1073/pnas.82.1.38 DO - 10.1073/pnas.82.1.38 ID - Srivastava1985 ER - TY - JOUR AU - Mamane, Y. AU - Petroulakis, E. AU - Rong, L. AU - Yoshida, K. AU - Ler, L. W. AU - Sonenberg, N. PY - 2004 DA - 2004// TI - eIF4E–from translation to transformation JO - Oncogene VL - 23 UR - https://doi.org/10.1038/sj.onc.1207549 DO - 10.1038/sj.onc.1207549 ID - Mamane2004 ER - TY - JOUR AU - Lee, S. AU - Kang, J. AU - Cho, M. AU - Seo, E. AU - Choi, H. AU - Kim, E. AU - Kim, J. AU - Kim, H. AU - Kang, G. Y. AU - Kim, K. P. PY - 2009 DA - 2009// TI - Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches JO - Int J Oncol VL - 34 ID - Lee2009 ER - TY - JOUR AU - Dejean, L. AU - Beauvoit, B. AU - Bunoust, O. AU - Guerin, B. AU - Rigoulet, M. PY - 2002 DA - 2002// TI - Activation of Ras cascade increases the mitochondrial enzyme content of respiratory competent yeast JO - Biochem Biophys Res Commun VL - 293 UR - https://doi.org/10.1016/S0006-291X(02)00391-1 DO - 10.1016/S0006-291X(02)00391-1 ID - Dejean2002 ER - TY - JOUR AU - Kinkade, C. W. AU - Castillo-Martin, M. AU - Puzio-Kuter, A. AU - Yan, J. AU - Foster, T. H. AU - Gao, H. AU - Sun, Y. AU - Ouyang, X. AU - Gerald, W. L. AU - Cordon-Cardo, C. AU - Abate-Shen, C. PY - 2008 DA - 2008// TI - Targeting AKT/mTOR and ERK MAPK signalling inhibits hormone-refractory prostate cancer in a preclinical mouse model JO - J Clin Invest VL - 118 ID - Kinkade2008 ER - TY - JOUR AU - Horimoto, M. AU - Resnick, M. B. AU - Konkin, T. A. AU - Routhier, J. AU - Wands, J. R. AU - Baffy, G. PY - 2004 DA - 2004// TI - Expression of uncoupling protein-2 in human colon cancer JO - Clin Cancer Res VL - 10 UR - https://doi.org/10.1158/1078-0432.CCR-04-0419 DO - 10.1158/1078-0432.CCR-04-0419 ID - Horimoto2004 ER - TY - JOUR AU - Lorenzo, M. AU - Valverde, A. M. AU - Teruel, T. AU - Alvarez, A. AU - Benito, M. PY - 1996 DA - 1996// TI - p21ras induced differentiation-related gene expression in fetal brown adipocyte primary cells and cell lines JO - Cell Growth Differ VL - 7 ID - Lorenzo1996 ER - TY - JOUR AU - Chen, Y. AU - Cairns, R. AU - Papandreou, I. AU - Koong, A. AU - Denko, N. C. PY - 2009 DA - 2009// TI - Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect JO - PLoS One VL - 4 UR - https://doi.org/10.1371/journal.pone.0007033 DO - 10.1371/journal.pone.0007033 ID - Chen2009 ER - TY - JOUR AU - Taetle, R. AU - Rosen, F. AU - Abramson, I. AU - Venditti, J. AU - Howell, S. PY - 1987 DA - 1987// TI - Use of nude mouse xenografts as preclinical drug screens: in vivo activity of established chemotherapeutic agents against melanoma and ovarian carcinoma xenografts JO - Cancer Treat Rep VL - 71 ID - Taetle1987 ER -