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Figure 3 | Molecular Cancer

Figure 3

From: Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth

Figure 3

Selective inhibition of K-Ras expression by A549 lung adenocarcinoma cells reduces COX activity, oxygen consumption and ATP. A549 cells were transfected with transfection reagent (TR) alone, control siRNA or siRNA specific for K-Ras for 72 hours and then examined for COX Vb protein expression (A and B), COX Vb mRNA expression (C), COX activity (D), oxygen consumption (E) and ATP (F). Data are expressed as the mean ± SD of three experiments. * p value <0.05.

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