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Figure 6 | Molecular Cancer

Figure 6

From: Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells

Figure 6

Overexpression of rab31 affects lung colonization and metastatic growth of human breast cancer cells. Stably transfected, lacZ-tagged, MDA-MB-231 cells were inoculated into nude mice via tail vein injection. Mice received either vector control cells (grey column, n = 7) or batch-transfected rab31 cells (green column, n = 7). Animals were sacrificed at day 35 after injection, lungs were collected and stained with X-Gal. Metastases were counted in lungs of the mice. Whisker box plots indicate the 25th and 75th percentile, the vertical bars indicate the 10th and 90th percentile. Results are expressed as the median number of metastases. The median value is indicated by a bar within the box. Statistically significant differences (p < 0.05) to the vector control group are indicated by an asterisk.

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