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Table 1 Rab31 overexpression reduces the adhesive capacity of human breast cancer cells in vitro

From: Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells

 

rab31 batch

rab31 high

rab31 medium

rab31 low

Col IV

82.3+/-4.0*

72.0+/-3.1*

82.4+/-4.6*

85.6+/-5.0*

Col I

84.8+/-3.0*

70.5+/-2.7*

87.4+/-4.2*

81.6+/-5.8*

Fn

84.7+/-3.2*

71.6+/-3.0*

93.4+/-7.1*

95.8+/-4.7*

Vn

82.3+/-3.3*

63.1+/-3.3*

83.8+/-4.3*

90.2+/-4.9*

Ln

81.4+/-5.4*

67.7+/-4.4*

91.1+/-8.6*

88.2+/-11.1*

  1. MDA-MB-231 cells were seeded on 96-well plates coated with the extracellular matrix proteins collagen type I (Col I), collagen type IV (Col IV), fibronectin (Fn), vitronectin (Vn) or laminin (Ln). After 2 h of cell cultivation, the number of adherent cells was monitored by the hexosaminidase activity assay. At least 5 independent experiments were performed in triplicates each. The results are given in % relative to the cell number of adherent vector–transfected control cells. The mean values +/- SEM are depicted. Statistically significant differences (p < 0.05) to the vector control group are indicated by an asterisk.
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Molecular Cancer

ISSN: 1476-4598