Figure 5
From: Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K
The effect of Coronin 3 expression on several proteolytic enzymes in gastric cancer cells. The expression of TIMP-2, MMP-9, and cathepsin K in gastric cancer cells was evaluated by Western blotting. β-actin was used as the internal control. The levels of TIMP-2, MMP-9, and cathepsin K protein in the MKN45-shRNA-LV and MKN28-pcDNA3.1-Coronin 3 cells were significantly different from those in the empty vector-transfected cells (p < 0.05).