miR-146a reduces monocyte migration. Monocyte migration against conditioned medium from control- or miR-146a-transfected SNU638 cells that were left untreated or stimulated with 25 μM LPA was followed over 8 hours. Migration of cells is shown relative to migration of untreated control cells. Monocyte migration against medium from LPA-stimulated SNU638 cells was increased compared to migration against medium from untreated cells, while monocyte migration against medium from miR-146a-transfected, LPA-stimulated cells was decreased compared to medium from control-transfected, LPA-stimulated cells. Data are shown as mean ± S.D. of four biological replicates. ** = P < 0.01, ns = non significant.