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Figure 2 | Molecular Cancer

Figure 2

From: Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis

Figure 2

Impact of CEACAM6 over-expression on proliferation and apoptosis in the Detroit 562 cell line. A) Rt-PCR analysis of CEACAM6 mRNA expression in pLV101 control and pLV101 CEA transduced Detroit 562 cells. B) CEACAM6 protein expression in control and pLV101 CEA transduced Detroit 562 cells. β-actin is provided as a reference for loading equivalence. C) BrdU incorporation in control (PLV101) and pLV101 CEA transduced Detroit 562 cells (n = 6). BrdU is reported as Absorbance Units/well (A450nm-A560nm). D) Percentage of total cells that express Annexin V in control (PLV101) and pLV101 CEA transduced Detroit 562 cells. Data presented as mean +/− sem of at least 3 independent experiments performed in triplicate. * P ≤ 0.05.

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