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Figure 2 | Molecular Cancer

Figure 2

From: Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status

Figure 2

Downstream PI3K and MAPK pathway activation. Melanoma cells were starved in 0.2% FBS overnight and then protein lysates were collected and evaluated by Western blot analysis for activation of ERK1/2 and Akt. Numerical values for the IC50 of E6201 for each cell line, as well as phosphorylation status scoring for both ERK1/2 and Akt is provided in tabular form.

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