Figure 7From: P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell linesSchematic representation of effect of P276-00 on cell cycle regulator and apoptosis in MCL. P276-00, a Cdk4-D1, Cdk1-B and Cdk9-T1 specific inhibitor showed potent antiprolifeartive effect in MCL cell lines by targeting positive and negative regulators of cell cycle with modulation of apoptosis.Back to article page