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Table 1 IC 50 (ÎĽmol/L) for P276-00 and roscovitine in Mantle cell lymphoma cell lines

From: P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines

Cell lines

P276-00

Roscovitine

48 h

96 h

48 h

96 h

Jeko-1

0.35 ± 0.047

0.21 ± 0.055

25.3 ± 1.83

18 ± 2.82

Mino

0.5 ± 0.28

0.25 ± 0.01

18.1 ± 4.38

14.56 ± 4.55

Rec-1

0.5 ± 0.24

0.33 ± 0.028

32 ± 1.0

40.1 ± 1.27

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Molecular Cancer

ISSN: 1476-4598