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Figure 4 | Molecular Cancer

Figure 4

From: Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system

Figure 4

In vitro effect of adenoviral vectors carrying the E1A gene. (a) Cell viability was determined by an MTT assay at 72 h after infection with recombinant adenoviral vectors (10 PFU/cell). Graphs are representative of three separate experiments. (b) Apoptosis was investigated using flow cytometric analysis at 72 h after infection with Ad315-E1A, Ad315-EGFP or H101 (10 PFU/cell). The bottom right quadrants in dot plots show the apoptosis of various cell lines infected with Ad315-E1A. Data are representative of three separate experiments.

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