Figure 5
From: IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation
IL-1β enhances invasiveness and proliferation of colon cancer cells. (A) Representative images of wounds at 0 and 48 h in the presence or absence of IL-1β. Confluent monolayers of HCT-116 cells were scraped by a pipette tip to generate wounds and then were cultured in the presence or absence of IL-1β for 48 h. (B) Relative wound width represented as percentages compared to the wound width at 0 h. (C) Proliferation of HCT-116 cells in the presence or absence of IL-1β as measured by cell count. Error bars represent SEM. *p < 0.05.