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Figure 1 | Molecular Cancer

Figure 1

From: Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Figure 1

Knockdown screening of MAPK-associated genes in pancreatic cancer cells. Proliferation of MIA PaCa-2, a pancreatic cancer cell line, transfected with siRNA targeting various genes associated with MAPK (indicated on the horizontal axis), was determined by MTT assay on day 5 post-transfection. Plotted values are expressed relative to cells infected with control siRNA to a nonspecific sequence (Nonsp). Plots represent an average of 2 independent experiments; each experiment includes data from 8 independent transfection wells. Knockdown of SON (closed column) showed the most remarkable anti-proliferative phenotype.

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Molecular Cancer

ISSN: 1476-4598