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Figure 2 | Molecular Cancer

Figure 2

From: Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Figure 2

A. Proliferation of pancreatic cancer cells (MIA PaCa-2 and PCI-35) and normally phenotypic duct epithelial cells (HPDE) transfected with siRNA against SON (siSON) or a nonspecific sequence (siNons) and measured by MTT assay. The plots represent an average of 2 independent experiments; experiment includes data from 8 independent transfection wells. B. Expression of SON in cells transfected with siSON or siNons is shown in immunoblots probed with anti-SON antibody (SON) or anti-beta actin antibody (ACTB). C. Colony formation assay of pancreatic cancer cells transfected with vectors expressing shRNA targeting SON (shSON) or a non-specific sequence (shNons).

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Molecular Cancer

ISSN: 1476-4598