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Figure 3 | Molecular Cancer

Figure 3

From: Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Figure 3

Immunohistochemical examination of SON expression in pancreatic cancer tissues. Diaminobenzidine and hematoxylin was used as a chromogen and a counter stain, respectively. A and B. Ductal adenocarcinomas (ducts labeled in C) strongly express SON in nuclei, more obviously than normal ductal cells (ducts labeled in N). The normal duct in panel B was partially (lower half) involved with carcinoma cells (original magnification, 100×). C. A high-powered view of ductal adenocarcinoma shows strong expression of SON in nuclei (original magnification, 200×). D. Pancreatic intraepithelial neoplasia, a precursor lesion of ductal adenocarcinoma, shows less obvious expression of SON (original magnification, 100×).

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