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Figure 7 | Molecular Cancer

Figure 7

From: Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico

Figure 7

Dynamic cross correlation maps between Cα atoms, of the wild type and mutated protein. Top left triangle represents the wild type, bottom right represents the Glu710Gly mutant. Subdomain decomposition is also indicated. Color coding for the correlation values is given on the bottom, negative values indicate anticorrelation, positive ones indicate direct correlation. Regions of interest are enclosed in blue rectangles and circles.

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