Figure 2From: The complexity of bladder cancer: long noncoding RNAs are on the stageLong noncoding RNA (lncRNA)-mediated signaling pathways in bladder cancer and its applications. (A) Oncogenic lncRNAs activate proliferative pathways, such as PI3K-AKT and Wnt/β-catenin pathways; lncRNAs such as UCA1, H19, MALAT1 and linc-UBC1 are overexpressed in bladder cancer and epigenetically regulate gene expression in concert with core cancer pathways during tumorigenesis. (B) LncRNA UCA1 as a biomarker for noninvasive detection in urine.Back to article page