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Figure 2 | Molecular Cancer

Figure 2

From: The complexity of bladder cancer: long noncoding RNAs are on the stage

Figure 2

Long noncoding RNA (lncRNA)-mediated signaling pathways in bladder cancer and its applications. (A) Oncogenic lncRNAs activate proliferative pathways, such as PI3K-AKT and Wnt/β-catenin pathways; lncRNAs such as UCA1, H19, MALAT1 and linc-UBC1 are overexpressed in bladder cancer and epigenetically regulate gene expression in concert with core cancer pathways during tumorigenesis. (B) LncRNA UCA1 as a biomarker for noninvasive detection in urine.

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