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Table 1 Percent apoptotic cells as measured by Caspase-3 activity in cells treated with gemcitabine

From: Inhibiting signal transducer and activator of transcription-3 increases response to gemcitabine and delays progression of pancreatic cancer

 

% apoptotic cells

 

Gemcitabine (ng/ml)

 

0

10

25

UK Pan-1/Control

0.38

0.97

3.14

UK Pan-1/shSTAT3.cl.8

3.1

24.4

35.6

PANC-1/Control

0.01

0.01

.02

PANC-1/shSTAT3.cl.22

4.7

6.0

55.4

MIA PaCa-2/Control

0.06

0.06

0.07

MIA PaCa-2/shSTAT3.cl.2

2.6

5.5

10.0

BxPC3/Control

0.04

0.17

0.12

BxPC3/shSTAT3.cl.21

0.4

1.6

5.7

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Molecular Cancer

ISSN: 1476-4598