Table 1 Clinicopathological correlation with AEG-1 in 93 cases of OSCC
Parameter | AEG-1 expression status | Fisher’s exact test | |
|---|---|---|---|
Low | High | ||
No. (%) | No. (%) | p value | |
Gender | Â | Â | Â |
Male | 46 (83.64%) | 33 (86.84%) | 0.773 |
Female | 9 (16.36%) | 5 (13.16%) | |
Age | Â | Â | Â |
>50 y/o | 36 (65.45%) | 20 (52.63%) | 0.282 |
<50 y/o | 19 (34.55%) | 18 (47.37%) | |
Location | Â | Â | Â |
Buccal mucosa | 22 (40.00%) | 18 (47.37%) | 0.307 |
Gingiva | 11 (20.00%) | 3 (7.89%) | Â |
Floor of the mouth | 1 (1.81%) | 2 (5.26%) | Â |
Lip | 0 (0%) | 2 (5.26%) | Â |
Tongue | 19 (34.55%) | 12 (31.58%) | Â |
Palate | 2 (3.64%) | 1 (2.64%) | Â |
Stage | Â | Â | Â |
I + II | 30 (54.55%) | 10 (26.32%) | 0.01 |
III + IV | 25 (45.45%) | 28 (73.68%) |  |
T | Â | Â | Â |
T1 + T2 | 31 (56.36%) | 22 (57.89%) | 1.000 |
T3 + T4 | 24 (43.64%) | 16 (42.11%) | |
N | Â | Â | Â |
N0 | 47 (85.45%) | 17 (44.74%) | <0.001 |
N1 + N2 + N3 | 8 (14.55%) | 21 (55.26%) | |
M | Â | Â | Â |
M0 | 54 (98.18%) | 34 (89.47%) | 0.155 |
M1 | 1 (1.82%) | 4 (10.53%) | Â |
Recurrence | Â | Â | Â |
Negative | 45 (81.82%) | 30 (78.95%) | 0.793 |
Positive | 10 (18.18%) | 8 (21.05%) | Â |
Differentiation | Â | Â | Â |
Well | 48 (87.27%) | 27 (71.05%) | 0.064 |
Moderate/poor | 7 (12.73%) | 11 (28.95%) | |
Alcohol | Â | Â | Â |
Negative | 24 (43.64%) | 10 (26.32%) | 0.125 |
Positive | 31 (56.36%) | 28 (73.68%) | |
Betel nut | Â | Â | Â |
Negative | 16 (29.09%) | 6 (15.79%) | 0.214 |
Positive | 39 (70.91%) | 32 (84.21%) | Â |
Cigarette | Â | Â | Â |
Negative | 14 (25.45%) | 8 (21.05%) | 0.805 |
Positive | 41 (74.55%) | 30 (78.95%) | |