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Figure 4 | Molecular Cancer

Figure 4

From: Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells

Figure 4

Functional effects of FBP2 on aerobic glycolysis. (A) Cellular ATP levels measured using a firefly luciferase-based ATP Assay Kit and normalised to controls showed that FBP2 overexpression inhibited ATP production (P < 0.05). (B) Lactate levels in cellular culture medium measured using a Lactic Acid Detection Kit and normalised to controls revealed that FBP2 overexpression inhibited lactate production (P < 0.05). (C) Western blot analysis showed inhibition of the Akt-mTOR pathway in BGC823 cells with pcDNA3.1-FBP2 plasmid compared to mock transfected cells.

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Molecular Cancer

ISSN: 1476-4598