Table 2 The RAD50 _rs17166050 genotypes/allele frequency distribution and logistic regression analysis (with odds ratio and 95% confidence interval) in laryngeal cancer (LC), multiple primary tumors with laryngeal cancer (MPT-LC), multiple primary tumors of head and neck (MPT) and controls
From: The MRN protein complex genes: MRE11 and RAD50 and susceptibility to head and neck cancers
Genotype/allele | Controls n (%) | LC n (%) | OR (95% CI) | MPT-LC n (%) | OR (95% CI) | MPT n (%) | OR (95% CI) |
|---|---|---|---|---|---|---|---|
GG | 233 (47) | 87 (50) | 1* | 50 (44) | 1* | 24 (35) | 1* |
GA | 195 (40) | 69 (39) | 1.06 (0.74-1.53) | 57 (50) | 0.73 (0.48-1.12) | 38 (56) | 0.53 (0.31-0.92) † |
AA | 66 (13) | 19 (11) | 1.30 (0.74-2.29) | 8 (6) | 1.78 (0.80-3.92) | 6 (9) | 1.13 (0.44-2.89) |
GA+AA | 261 (52) | 88 (50) | 1.11 (0.78-1.56) | 65 (57) | 0.86 (0.57-1.30) | 44 (65) | 0.61 (0.36-1.04) |
G | 661 (66) | 243 (69) | 1* | 157 (68) | 1* | 86 (63) | 1* 0.85 |
A | 327 (34) | 107 (31) | 1.12 (0.87-1.46) | 73 (22) | 1.06 (0.78-1.45) | 50 (37) | (0.59-1.24) |