Figure 3From: Reversal of chemosensitivity and induction of cell malignancy of a non-malignant prostate cancer cell line upon extracellular vesicle exposureExtracellular vesicle-mediated changes in cellular protein expression. EVs were isolated from DU145 and PrECs and resuspended in PBS. EVs were co-cultured with DU145 cells and whole cell lysates were prepared for Western blot analysis as reported. Western blot analysis results show that DU145 cells co-cultured with self-EVs have enhanced expression of STAT3, while co-culture with PrEC EVs leads to increased expression of SOCS3.Back to article page