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Figure 2 | Molecular Cancer

Figure 2

From: Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

Figure 2

Tumor development in SCID mice. Starting on day 14 (vertical broken line), mice received intraperitoneal (●) and intratumoral (■) injections of PTX as well as intratumoral (▲) injections of PBS at three-day-intervals. From day 20 on the differences between the intratumoral and the intraperitoneal treated PTX receiving groups were significant (P < 0.05). Similarly, differences were observed when comparing the intratumoral PTX and the intratumoral PBS groups, where tumor sizes were significantly different (p<0.05) from day 20 on. In addition, at all time points measured, there were no significant differences in tumor size between the intratumoral PBS and the ip PTX group (p>0.05). Data represent mean tumor volume ± SD.

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Molecular Cancer

ISSN: 1476-4598