Skip to main content

Advertisement

Figure 2 | Molecular Cancer

Figure 2

From: The soluble Decoy Receptor 3 is regulated by a PI3K-dependent mechanism and promotes migration and invasion in renal cell carcinoma

Figure 2

DcR3 promotes invasiveness in RCC cells. (A,B) Boyden chamber assay of ACHN and 769-P cells transfected with two different DcR3-specific siRNAs or a non-specific siRNA (scram) (A) or stably overexpressing DcR3 or an empty vector control (neo) (B). Bars indicate the percentage of cellular invasion in correlation to control cells. Invaded cells were counted in five representative fields (mean ± SEM; n=3, **p<0.01, ***p<0.001; T-test). Representative images are shown (magnification: 200×). (C) Spheroid assay of ACHN and 769-P cells stably overexpressing DcR3 or an empty control vector (neo). Bars indicate the percentage of cell invasion in relation to cells stably transfected with an empty control vector (mean ± SEM; n=3; *p<0.05, T-test). Representative images are shown (magnification: 40×).

Back to article page