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Table 2 Mitochondrial membrane potential ( ΔΨm) of ZD6474 and/or UV-B treated breast cancer cells

From: Targeted therapy against EGFR and VEGFR using ZD6474 enhances the therapeutic potential of UV-B phototherapy in breast cancer cells

Cell line

Treatment

M1 (%)a

M2 (%)b

MCF-7

Control

95.37 ± 2.45

4.62 ± 2.45

ZD6474

85.78 ± 3.16

14.22 ± 3.16

UVB

81.07 ± 3.64

18.93 ± 3.65

ZD6474 + UV-B

65.81 ± 3.89

35.52 ± 5.87

MDA-MB-468

Control

93.08 ± 1.36

6.92 ± 1.66

ZD6474

87.47 ± 1.04

12.53 ± 1.27

UVB

69.33 ± 2.92

30.66 ± 1.15

 

ZD6474 + UV-B

54.06 ± 5.08

45.93 ± 6.34

  1. aPercentage (%) cells in M1 population was calculated by gating cells at higher membrane potential. bPercentage (%) cells in M2 population was calculated by gating cells at reduced membrane potential.
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Molecular Cancer

ISSN: 1476-4598