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Table 1 Associations between miR-451 expression and clinical characteristics in patients with nasopharyngeal carcinoma

From: MiR-451 inhibits cell growth and invasion by targeting MIF and is associated with survival in nasopharyngeal carcinoma

Characteristics No. of patients Expression of miR-451 P value
   Low, n (%) High, n (%)  
Age     
≤ 45 yr 136 66 (47) 70 (50) 0.63
> 45 yr 144 74 (53) 70 (50)  
Sex     
Male 206 100 (71) 106 (76) 0.42
Female 74 40 (29) 34 (24)  
WHO Type     
I + II 11 4 (3) 7 (5) 0.36
III 269 136 (97) 133 (95)  
VCA-IgA     
< 1:80 43 21 (15) 22 (16) 0.87
≥ 1:80 237 119 (85) 118 (84)  
EA-IgA     
< 1:10 71 37 (26) 34 (24) 0.68
≥ 1:10 209 103 (74) 106 (76)  
T Stage     
T1-T2 142 70 (50) 72 (51) 0.81
T3-T4 138 70 (50) 68 (49)  
N Stage     
N0 42 89 (64) 85 (61) 0.62
N1-N3 238 51 (36) 55 (39)  
TNM Stage     
I-II 91 49 (35) 42 (30) 0.37
III-IV 189 91 (65) 98 (70)  
  1. VCA-IgA: viral capsid antigen immunoglobulin A; EA-IgA: early antigen immunoglobulin A. All patients were restaged according to the 7th edition of the AJCC Cancer Staging Manual.