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Table 3 RT-qPCR results mean fold variation for RRas1, RRas2 and RRas3

From: R-RAS2 overexpression in tumors of the human central nervous system

     RRas1 RRas2 RRas3
Histo-pathology Grade1 Gender Age Fold variation2 Standard deviation3 Fold variation2 Standard deviation3 Fold variation2 Standard deviation3
Brain tissue - Female 55 1,003 0,151 1,000 0,150 1,000 0,150
Meningioma, fibroblastic I Female 56 3,054 1,004 3,596 1,183 0,254 0,083
Meningioma, fibroblastic I Female 51 7,878 0,335 - - 0,522 0,022
Meningioma I Male 71 2,106 0,181 19,016 1,632 1,040 0,089
Meningioma, meningothelial I Female 56 4,565 1,672 8,514 3,118 0,262 0,096
Meningioma, secretory I Female 41 1,422 0,160 25,092 2,825 0,083 0,009
Meningioma I Female 42 5,798 1,248 4,779 1,029 0,263 0,057
Meningioma, fibroblastic I Male 39 - - 13,533 4,059 0,592 0,178
Meningioma, fibroblastic I Male 43 1,944 0,640 14,801 4,873 0,133 0,044
Astrocytoma I Female 27 4,550 0,691 2,253 0,342 - -
Meningioma I Female 83 3,043 0,414 10,352 1,407 0,251 0,034
Meningioma I Male 68 3,027 1,174 6,131 2,378 0,202 0,078
Meningioma I Female 45 6,406 5,394 2,441 2,056 0,526 0,443
Meningioma I Female 61 4,791 0,024 8,719 0,043 0,352 0,002
Meningioma I Male 44 5,386 0,485 10,301 0,927 0,688 0,062
Meningioma, atypical II Male 67 2,365 0,154 14,736 0,962 0,103 0,007
Hyperplasia II Male 45 0,636 0,043 14,934 1,004 0,075 0,005
Oligoastrocytoma II Female 37 - - 6,902 3,282 - -
Astrocytoma II Male 26 0,503 0,156 21,775 6,753 0,058 0,018
Meningioma, meningothelial II Female 56 2,388 1,323 4,122 2,284 0,312 0,173
Astrocytoma II Female 53 0,928 0,287 22,939 7,099 0,042 0,013
Meningioma, atypical II Male 73 1,757 1,006 7,157 4,096 0,129 0,074
Meningioma, atypical II Female 48 4,151 1,897 4,118 1,882 0,512 0,234
Oligodendroglioma II Male 33 1,545 0,269 10,723 1,868 0,211 0,037
Astrocytoma, anaplastic III Male 36 1,768 0,583 2,815 0,929 0,403 0,133
Astrocytoma, anaplastic III Male 39 1,290 0,236 0,559 0,102 0,702 0,128
Astrocytoma III Male 30 1,721 0,875 8,782 4,464 0,128 0,065
Oligodendroglioma, anaplastic III Female 41 0,814 0,185 0,579 0,131 - -
Ependymoma of brain, anaplastic III Female 49 0,895 0,055 2,548 0,155 0,266 0,016
Oligoastrocytoma, anaplastic III Male 41 1,211 0,175 3,254 0,470 0,432 0,062
Oligodendroglioma, anaplastic III Female 51 0,521 0,075 5,038 0,721 0,165 0,024
Oligodendroglioma, anaplastic III Female 44 1,707 0,509 7,080 2,110 0,119 0,035
  1. 1Classified according to the WHO criteria.
  2. 2All results were calculated as the mean of the three measurements performed on each sample and subsequently normalized to the expression in the non tumoral sample.
  3. 3Standard deviation of the three measurements performed on each sample.