R-RAS2 overexpression in tumors of the human central nervous system

Gutierrez-Erlandsson, Sylvia; Herrero-Vidal, Pedro; Fernandez-Alfara, Marcos; Hernandez-Garcia, Susana; Gonzalo-Flores, Sandra; Mudarra-Rubio, Alberto; Fresno, Manuel; Cubelos, Beatriz

doi:10.1186/1476-4598-12-127

Molecular Cancer

Table 3 RT-qPCR results mean fold variation for RRas1, RRas2 and RRas3

From: R-RAS2 overexpression in tumors of the human central nervous system

				RRas1		RRas2		RRas3
Histo-pathology	Grade¹	Gender	Age	Fold variation²	Standard deviation³	Fold variation²	Standard deviation³	Fold variation²	Standard deviation³
Brain tissue	-	Female	55	1,003	0,151	1,000	0,150	1,000	0,150
Meningioma, fibroblastic	I	Female	56	3,054	1,004	3,596	1,183	0,254	0,083
Meningioma, fibroblastic	I	Female	51	7,878	0,335	-	-	0,522	0,022
Meningioma	I	Male	71	2,106	0,181	19,016	1,632	1,040	0,089
Meningioma, meningothelial	I	Female	56	4,565	1,672	8,514	3,118	0,262	0,096
Meningioma, secretory	I	Female	41	1,422	0,160	25,092	2,825	0,083	0,009
Meningioma	I	Female	42	5,798	1,248	4,779	1,029	0,263	0,057
Meningioma, fibroblastic	I	Male	39	-	-	13,533	4,059	0,592	0,178
Meningioma, fibroblastic	I	Male	43	1,944	0,640	14,801	4,873	0,133	0,044
Astrocytoma	I	Female	27	4,550	0,691	2,253	0,342	-	-
Meningioma	I	Female	83	3,043	0,414	10,352	1,407	0,251	0,034
Meningioma	I	Male	68	3,027	1,174	6,131	2,378	0,202	0,078
Meningioma	I	Female	45	6,406	5,394	2,441	2,056	0,526	0,443
Meningioma	I	Female	61	4,791	0,024	8,719	0,043	0,352	0,002
Meningioma	I	Male	44	5,386	0,485	10,301	0,927	0,688	0,062
Meningioma, atypical	II	Male	67	2,365	0,154	14,736	0,962	0,103	0,007
Hyperplasia	II	Male	45	0,636	0,043	14,934	1,004	0,075	0,005
Oligoastrocytoma	II	Female	37	-	-	6,902	3,282	-	-
Astrocytoma	II	Male	26	0,503	0,156	21,775	6,753	0,058	0,018
Meningioma, meningothelial	II	Female	56	2,388	1,323	4,122	2,284	0,312	0,173
Astrocytoma	II	Female	53	0,928	0,287	22,939	7,099	0,042	0,013
Meningioma, atypical	II	Male	73	1,757	1,006	7,157	4,096	0,129	0,074
Meningioma, atypical	II	Female	48	4,151	1,897	4,118	1,882	0,512	0,234
Oligodendroglioma	II	Male	33	1,545	0,269	10,723	1,868	0,211	0,037
Astrocytoma, anaplastic	III	Male	36	1,768	0,583	2,815	0,929	0,403	0,133
Astrocytoma, anaplastic	III	Male	39	1,290	0,236	0,559	0,102	0,702	0,128
Astrocytoma	III	Male	30	1,721	0,875	8,782	4,464	0,128	0,065
Oligodendroglioma, anaplastic	III	Female	41	0,814	0,185	0,579	0,131	-	-
Ependymoma of brain, anaplastic	III	Female	49	0,895	0,055	2,548	0,155	0,266	0,016
Oligoastrocytoma, anaplastic	III	Male	41	1,211	0,175	3,254	0,470	0,432	0,062
Oligodendroglioma, anaplastic	III	Female	51	0,521	0,075	5,038	0,721	0,165	0,024
Oligodendroglioma, anaplastic	III	Female	44	1,707	0,509	7,080	2,110	0,119	0,035

¹Classified according to the WHO criteria.
²All results were calculated as the mean of the three measurements performed on each sample and subsequently normalized to the expression in the non tumoral sample.
³Standard deviation of the three measurements performed on each sample.

Back to article page

ISSN: 1476-4598

Contact us

General enquiries: journalsubmissions@springernature.com