Figure 1

Global expression patterns of ucRNAs in human prostate cancer. (A) The summary chart shows percent and number (in parenthesis) of ucRNAs found to be altered in human prostate cancer for the various class comparisons at the indicated cutoff. EPE = extraprostatic extension of the disease and SVI = seminal vesicle invasion. (B) Most significantly altered ucRNAs in tumor and (C) by clinical characteristics of the prostate cancer patients. The P < 0.001 (all FDR < 5%) significance level defines an altered transcript in (B) and (C). Class comparisons in (A) and (C): Tumor vs. normal; high (≥7) vs. low (≤6) Gleason sum score; pT3 vs. pT2 (stage); EPE yes vs. no; SVI yes vs. no; African-American vs. European-American (race); ≤ age 60 versus ≥ age 61 (age at prostatectomy).