Figure 3
From: Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer
Lack of association between ucRNA expression and the expression of the respective “host” mRNAs in prostate tumors. Shown is the distribution curve of the Pearson correlation coefficients between tumor-altered ucRNAs and the corresponding UCR-encoded mRNAs. The correlation coefficient for the ucRNA-mRNA pairs (n = 146) are clustered within the −0.2 to 0.2 range, independent whether pairs are sense (blue) or antisense (red) transcribed. UCR-encoded mRNAs are defined as mRNA transcripts with a coding region that at least partially overlaps with the UCR locus. Tumor-altered ucRNAs were defined as being differently expressed between tumor and adjacent non-cancerous tissue at the P ≤ 0.01 significance level.