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Table 2 Phospho-kinases correlated with radiosensitivity in HNSCC

From: Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines

Phospho-kinase

Condition

Spearman correlation coefficient

P-value

Src(Y419)

Expression in control

0.67

0.049

Expression after RT

0.75

0.019

STAT5A(Y699)

Expression in control

0.70

0.036

Yes(Y426)

Expression in control

0.67

0.050

AKT(S437)

Relative expression after RT

0.67

0.050

MSK1/2(S376/S360)

Expression after RT

0.67

0.050

Lyn(Y397)

Expression after RT

0.70

0.036

Fyn(Y420)

Expression after RT

0.70

0.036

Hck(Y411)

Expression after RT

0.72

0.030

STAT6(Y641)

Expression after RT

0.67

0.050

  1. RT: 4 Gy of radiotherapy.
  2. Expression in control or after RT: absolute expression level in control or 1 h after RT.
  3. Relative expression after RT: expression after radiotherapy divided by expression in control.
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Molecular Cancer

ISSN: 1476-4598