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Figure 4 | Molecular Cancer

Figure 4

From: Asymmetric segregation of template DNA strands in basal-like human breast cancer cell lines

Figure 4

Asymmetric segregation of template DNA is correlated with invasion and migration abilities. (A-C) The breast cancer cell lines were subjected to invasion and migration assays, and the number of cells that invaded (A) and migrated (B) are shown. Experiments were performed in triplicates and in at least two independent assays. The breast cancer cell lines were divided into two groups according to the percentage of BrdU asymmetric division observed, high asymmetry (mean, ≥0.5%) and low asymmetry (mean, <0.5%). (C) Representative images of invaded MDA-MB-231 and T47D cells, fixed and stained with crystal violet, are shown.

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