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Figure 5 | Molecular Cancer

Figure 5

From: Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a

Figure 5

Effect of serotonin and FOXO3a knockdown in serum-deprived Huh7 cells. (A) Mean ± SD relative cell viability of serum-deprived Huh7 cells cultured in the presence of serotonin (5-HT) and transfected with Negative control siRNA (NC-siRNA) or FOXO3a-siRNA; 5-HT+NC-siRNA vs. 5-HT+ FOXO3a-siRNA, **P < 0.01, two-way ANOVA. (B) EdU staining patterns of serum-deprived Huh7 cells transfected with Negative control siRNA or FOXO3a-siRNA after 48h incubation with serotonin (5-HT).(C) Flow cytometry cell cycle analysis of serum-deprived Huh7 cells transfected with NC-siRNA, FOXO3a-siRNA or cultured with 5-HT.

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Molecular Cancer

ISSN: 1476-4598