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Table 1 List of 40 lncRNAs differentially expressed in RCC from the present work: 29 intronic lncRNAs and 11 lincRNAs (FDR <5%; >1.5-fold change)

From: Expression analysis and in silico characterization of intronic long noncoding RNAs in renal cell carcinoma: emerging functional associations

GenBank accession of probe§

lncRNA type

RefSeq of host gene

Host gene symbol

Genomic coordinates

FDR (%)

Fold change of lncRNA

Average fold change of host gene†

AW835362

Intronic

NM_001553

IGFBP7

chr4:57928550-57929060

0.00

4.88

-1.15 (2/4)

AW881130

Intronic

NM_006868

RAB31

chr18:9711672-9712160

0.00

3.72

2.56 (5/5)

BF881464

Intronic

NM_004930

CAPZB

chr1:19724054-19724494

0.00

2.03

1.34 (3/5)*

AW846722

Intronic

NM_024113

C11orf49

chr11:47169567-47169799

0.00

2.02

-0.34 (2/4)

AW815357

Intronic

NM_153326

AKR1A1

chr1:46029945-46030338

0.00

1.77

-2.20 (3/3)

AW937741

Intronic

NM_003137

SRPK1

chr6:35819568-35820194

2.46

1.7

-1.37 (3/4)

BF350736

Intronic

NM_025228

TRAF3IP3

chr1:209954933-209955401

1.93

1.65

1.39 (4/4)

CK327196

Intronic

NM_002581

PAPPA

chr9:119104917-119105402

1.86

1.63

-3.49 (5/5)

BF743551

Intronic

NM_005720

ARPC1B

chr7:98991157-98991537

1.37

1.6

2.90 (5/5)

AW748493

Intronic

NM_001098634

RBM47

chr4:40563872-40564416

3.16

-1.52

-1.82 (4/4)

CK327206

Intronic

NM_015995

KLF13

chr15:31628837-31629268

2.46

-1.53

1.19 (1/4)

CK327137

Intronic

NM_173355

UPP2

chr2:158886308-158886559

1.37

-1.55

-6.05 (1/2)

BE168993

Intronic

NM_005882

MAEA

chr4:1318234-1318651

1.68

-1.56

-1.63 (2/4)

BE181783

Intronic

NM_001893

CSNK1D

chr17:80226176-80226555

0.75

-1.63

-1.28 (3/3)*

AW836810

Intronic

NM_000314

PTEN

chr10:89630175-89630699

0.00

-1.63

1.74 (4/4)

BG010306

Intronic

NM_005474

HDAC5

chr17:42175003-42175469

0.75

-1.66

0.00 (0/3)

BF327015

Intronic

NM_003298

NR2C2

chr3:15052840-15053222

0.00

-1.7

-0.34 (0/5)

BF882783

Intronic

NM_004924

ACTN4

chr19:39203995-39204367

0.75

-1.74

-0.29 (1/5)

BF357721

Intronic

NM_002755

MAP2K1

chr15:66764897-66765436

0.00

-1.78

1.52 (3/4)

BF360792

Intronic

NM_020387

RAB25

chr1:156032114-156032418

0.75

-1.79

-5.17 (4/4)

CK327077

Intronic

NM_001170704

MBNL3

chrX:131621693-131622042

0.00

-1.9

-0.79 (0/5)

CK327106

Intronic

NM_005781

TNK2

chr3:195591793-195592189

0.00

-1.95

-1.16 (4/4)*

BF768459

Intronic

NM_004924

ACTN4

chr19:39200205-39200785

0.00

-2.01

-0.29 (1/5)*

BF368747

Intronic

NM_006516

SLC2A1

chr1:43409776-43410148

0.00

-2.01

4.43 (5/5)

BE080597

Intronic

NM_002829

PTPN3

chr9:112237298-112237614

0.00

-2.13

-2.15 (5/5)

BF332192

Intronic

NM_017890

VPS13B

chr8:100419550-100419768

0.00

-2.13

1.37 (3/5)

BE168995

Intronic

NM_018253

YY1AP1

chr1:155656314-155656660

0.00

-2.23

n.d.

CK327034

Intronic

NM_015575

GIGYF2

chr2:233592945-233593379

0.00

-2.45

1.16 (2/4)

BF368584

Intronic

NM_006260

DNAJC3

chr13:96432041-96432369

0.00

-2.81

1.74 (1/1)

BF368636

lincRNA1 RefSeq ncRNA

NR_028288

TCL6

chr14:96131134-96131552

0.00

1.92

-

AW880409

lincRNA2 RefSeq ncRNA

NR_003255 and NR_001564

TSIX and XIST

chrX:73042786-73043127

1.95

1.74

-

AW880864

lincRNA3

n.a.

n.a.

chr9:18430899-18431447

0.41

1.68

-

BF987841

lincRNA4

n.a.

n.a.

chr14:53107162-53107542

1.12

1.64

-

AW880828

lincRNA5

n.a.

n.a.

chr2:26955660-26956225

0.78

1.63

-

BF333219

lincRNA6

n.a.

n.a.

chr12:49324983-49325465

0.75

-1.63

-

BG009895

lincRNA7

n.a.

n.a.

chr21:19119867-19120311

0.00

-1.74

-

BE710971

lincRNA8

n.a.

n.a.

chr17:18176339-18176682

0.00

-1.93

-

BE718437

lincRNA9

n.a.

n.a.

chr17:56595754-56596085

0.00

-1.94

-

BF333731

lincRNA10

n.a.

n.a.

chr17:62118605-62119046

0.00

-2.19

-

AW996872

lincRNA11

n.a.

n.a.

chr15:58887770-58888280

0.00

-2.45

-

  1. § Probes are double-stranded cDNA, with the sequences that are indicated in the EST accession numbers from GenBank.
  2. † Host protein-coding genes expression from a meta-analysis of ccRCC gene expression studies [54–58] obtained with the Oncomine™ Software tool: average fold change (FC) values in tumor relative to nontumor tissues of all studies are shown. The numbers in bold indicate FC values in the range -1.5 > FC > 1.5. The numbers in parenthesis represent: number of studies with significant differential expression of that gene/number of studies that have detected the expression of that gene.
  3. * For this protein-coding gene more than one probe was present in some of the studies, and these additional probes showed an opposite expression pattern in the Oncomine Software. We show the most frequent pattern for this gene among all studies.