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Figure 2 | Molecular Cancer

Figure 2

From: RETRACTED ARTICLE: α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway

Figure 2

α-santalol inhibits cell growth in both HUVEC and PC-3 cells. (A) MTT assays of HUVEC with α-santalol, vandetanib or sunitinib, respectively. (B) MTT assays of PC-3 cells with α-santalol, vandetanib or sunitinib, respectively. (C) α-santalol inhibits the VEGF induced proliferation of endothelial cells. (D) BrdU cell proliferation enzyme linked immunosorbent assay of HUVEC with α-santalol. (E) LDH cytotoxicity assay of HUVEC with α-santalol. Values are mean ± SEM (n = 6) of three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001 versus vehicle control. #p < 0.001 versus VEGF stimulated group.

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