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Figure 6 | Molecular Cancer

Figure 6

From: Loss of MEF2D expression inhibits differentiation and contributes to oncogenesis in rhabdomyosarcoma cells

Figure 6

Expression of MEF2D inhibits proliferation, migration and anchorage independent growth of SJRH30 cells. A. MEF2D inhibits the proliferation of RH30 cells. Cells were seeded at equivalent densities and harvested for cell counts every two days. Error bars, SD. B. MEF2D inhibits the migration of RH30 cells. Monolayer of confluent cultures were lightly scratched with a pipette tip and phase contrast images were taken immediately after wounding (0 h) or at indicated times. Left panel: images were taken at 100X magnification and scale bars represent 10 μms. Right panel: data were quantified with a statistical evaluation of the distance between the borders (dotted lines, left panel) in three independent assays. Error bars, SD. C. MEF2D inhibits anchorage independent growth of RH30 cells. Soft agar colony formation was assayed in RH30 cells expressing MEF2D or vector control. Left panel: images are as described in B. Right panel: three independent assays were quantified. Error bars, SD.

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