Table 1 Univariate and multivariate cox proportional hazards regression models for estimating overall survival

Univariate analysis

Overall survival

Age (<60 y vs ≥ 60 y)

0.633

0.282 to 1.419

0.267

Gender (male vs female)

1.713

0.763 to 3.844

0.192

Smoking history (smoker vs nonsmoker)

0.643

0.295 to 1.401

0.267

Alcohol history (drinker vs nondrinker)

0.718

0.302 to 1.709

0.454

Tumor grade

2.096

1.283 to 3.425

0.003

TNM stage

1.784

1.181 to 2.696

0.006

Lymph node metastasis (pN0 vs pN1 to pN2)

2.514

1.153 to 5.481

0.020

TGM3 expression (high vs low)

0.191

0.072 to 0.506

0.001

Disease site

1.023

0.637 to 1.660

0.926

Multivariate analysis

Overall survival

Tumor grade

1.737

1.042 to 2.895

0.034

TNM stage

1.325

0.806 to 2.177

0.267

Lymph node metastasis (pN0 vs pN1 to pN2)

1.515

0.586 to 3.909

0.391

TGM3 expression (high vs low)

0.286

0.103 to 0.796

0.016