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Figure 6 | Molecular Cancer

Figure 6

From: DKK1 promotes hepatocellular carcinoma cell migration and invasion through β-catenin/MMP7 signaling pathway

Figure 6

DKK1 regulates β-catenin expression through the non-canonical Wnt pathway. A: Restoration of DKK1 promoted the mRNA expression of β-catenin in HepG2 cells. B: Knockdown of DKK1 attenuated β-catenin mRNA expression in Bel7402 cells. C: Restoration of DKK1 promoted the protein levels of β-catenin and c-Myc in HepG2 cells. D: Knockdown of DKK1 attenuated the protein levels of β-catenin and c-Myc in Bel7402 cells. E: IWP-2 attenuated the positive effect of DKK1 on β-catenin expression in HepG2 cells. F: Treatment with GSK3β inhibitor LiCl restored the expression of β-catenin in Bel7402 cells.

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