Figure 6From: Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheresEGFR and EGFRvIII expression in primary BT and corresponding NS cultured in different conditions. A) The upper part shows mRNA levels of EGFR in primary tumors and corresponding NS; the lower part shows the presence of wild type EGFR and/or the mutant EGFRvIII: BT462 displays a gradual appearance of EGFRvIII in modified medium, whereas BT470 shows the presence of the mutant form in primary tumor and in NS cultured in complete medium; B) Immuno-histochemistry on tumors specimens shows high levels of EGFR in both tumors.Back to article page