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Figure 3 | Molecular Cancer

Figure 3

From: Id4 dependent acetylation restores mutant-p53 transcriptional activity

Figure 3

Id4 regulates p53 expression and cellular localization. Analysis of p53 protein (A) expression in L, L-Id4, D and D + Id4 cells. The western blot analysis shown in panel A is the representative of three different experiments. B. Immuno-cytochemical localization of p53 in L, L-Id4, D and D + Id4 cells. Nuclear and cytoplasmic (arrows) expression of p53 is clearly evident in L, L-Id4 and D cells. Whereas p53 is primarily nuclear in D + Id4 cells (arrows). Red: p53, Blue: DAPI. Representative images are shown.

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