uPA putative binding sites for miR-193a located in the 3′-UTR mRNA and its phylogenetically conservation. (A) 3′-UTR uPA mRNA displays two putative binding sites for miR-193a. (B) The complementarity between miR-193a and the putative uPA 3′-UTR target sites are shown. The conserved bases of the putative miR-193a target sequence are also shown. hsa, Homo sapiens; ptr, P. troglodytes (chimpanzee); mmu, M. musculus (mouse); rno, R. norvegicus (rat); cfa, C. familiaris (dog).