miR-193a expression analysis by Real-Time PCR in tumoral tissues from biopsy samples of HCC patients. (A) The level of mature miR-193a is generally down-regulated in HCC compared with the corresponding PT tissues average RQPT = 5.53 ± 0.93, RQHCC = 3.27 ± 0.77; p < 0.05. (B) miR-193a expression level in HCCs developed in non-cirrhotic and (C) cirrhotic liver. (D) Cirrhotic HCCs stratified on the basis of the type of hepatitis viral infections. The class of HCV showed the lowest average R (average R = 0.338; p < 0.01 in a t-Test analysis for single group mean with expected value = 1).