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Figure 5 | Molecular Cancer

Figure 5

From: miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression

Figure 5

miR-133b regulates motility of CRC cells. (A) The transwell invasion and a migration assays were used to detect the motility of SW-480 and SW-620 cells transfected with miR-133b mimic, miR-133b inhibitor, siCXCR4 or their corresponding negative controls. (B) The cells that invaded or migrated to the lower upside were counted using a microscope. Original magnification: 200×. (C) Using a wound healing assay, the cell motilities of SW-480 and SW-620 cells transfected with the miR-133b mimic, miR-133b inhibitor, siCXCR4 or their corresponding negative controls were observed at 0, 24 and 48 hours following wounding by a pipette tip. Original magnification: 100×.

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