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Figure 6 | Molecular Cancer

Figure 6

From: In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133high to CD133low phenotype and reduces the CD133-related invasiveness

Figure 6

PLC-β2 and invasiveness of CD133lowcells. (A) Immunochemical analysis of immunoprecipitates with the anti-PLC-β2 antibody from CD133low cells transfected with siRNAs specific for PLC-β2 (PLC-β2 siRNAs). A non-silencing scramble siRNAs was used as a control (ctrl siRNAs). Lysates from the same cells were analyzed for β-tubulin content, as internal control of processed proteins. (B) Cytofluorimetrical analysis of surface expression of CD133 by direct staining with PE-conjugated 293C3 antibody and (C) dynamic monitoring of invasion through Matrigel using the xCELLigence system of transfected cells. Error bars indicate ± SD. All the data are representative of three separate experiments.

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Molecular Cancer

ISSN: 1476-4598