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Figure 3 | Molecular Cancer

Figure 3

From: Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas

Figure 3

Effects of CAFs (CAF1 and CAF2 cells) on the invasive potential of pancreatic cancer cells. CAF1 (high PDPN-expressing cells) promoted the migration (A, B) and invasion (C, D) of PANC-1, SUIT-2, and KP-2 cells compared with CAF2 (PDPN– cells). Significant differences between sample means are indicated as *P < 0.05, **P < 0.01. (B, D) Representative photomicrographs of migrating (B) and invading (D) cancer cells co-cultured with CAFs (hematoxylin and eosin staining; original magnification × 40).

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