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Figure 4 | Molecular Cancer

Figure 4

From: Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas

Figure 4

Effects of sorted CAFs on the invasiveness of pancreatic cancer cells. PDPN+ CAFs promoted the migration (A) and invasion (B) of PANC-1 and SUIT-2 cells compared with PDPN– CAFs. The P values for the migration assays were: P = 0.0001 (PANC-1 with CAF3), P = 0.0003 (PANC-1 with CAF4), P = 0.0034 (SUIT-2 with CAF3), and P = 0.0058 (SUIT-2 with CAF4). The P values for the invasion assays were: P = 0.0013 (PANC-1 with CAF3), P = 0.0022 (PANC-1 with CAF4), P = 0.0065 (SUIT-2 with CAF3), and P = 0.0013 (SUIT-2 with CAF4). Significant differences between sample means are indicated as **P < 0.01.

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