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Figure 1 | Molecular Cancer

Figure 1

From: MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1

Figure 1

miR-497 expression is significantly associated with risk and survival in a neuroblastoma cohort (n=143). (A) Box and whiskers plots represent the expression of miR-497 in a cohort of 143 primary neuroblastoma tumors. Samples are grouped according to known risk factors and expression compared in each of; MYCN amplified versus Non MYCN amplified or Stage 4 versus INSS Stage 1,2,3,4S. Statistical differences in median expression were analysed using two sided Mann–Whitney U tests. Dark shading indicates known higher risk factor. HR= Hazard Ratio. (B) Kaplan-Meier plots for event free survival (EFS) and overall survival (OS) in 143 neuroblastoma patients. P values were obtained using log-rank test.

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Molecular Cancer

ISSN: 1476-4598