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Table 1 Clinico-pathological characteristics of esophageal cancer patients for immunohistochemical investigation

From: IL-6 expression predicts treatment response and outcome in squamous cell carcinoma of the esophagus

  No. of patients  
  IHC-IL-6(-) IHC- IL-6 (+) p value
patients 85 88  
Age    
> = 56y/0 43 44 0.938
<56y/o 42 44  
Location    
Upper third 22 26 0.498
Middle third 48 42  
Lower third 15 20  
Tumor stage    0.041*
I-II 28 17  
III-IV 57 71  
LN metastasis    0.246
negative 27 21  
positive 58 67  
P-stat3 staining    <0.0001*
negative 71 20  
positive 14 68  
Response to Neoadjuvant Tx    0.0001*
Response 69 47  
Non- response 16 41  
Surgery s/p Neoadjuvant Tx    0.145
Yes 31 24  
No 54 64  
Local-regional Recurrence /persistent    <0.0001*
No 44 16  
Yes 41 72  
Distant metastasis    0.0003*
negative 58 36  
positive 27 52  
  1. Abbreviations: Neoadjuvant Tx = neoadjuvant chemoradiotherapy.