Figure 5

ERα/caveolin-1 complex formation in response to E2, TAM and RAL treatment in T47D:A18/PKCα tumors. A. Representative western blot of co-IP experiments in T47D:A18/PKCα and T47D:A18/neo tumor extracts as detailed in materials and methods. B. Densitometric quantification of three co-IP experiments from three independent tumors for each group. Error bars represent SEM. *, P < 0.05 compared to all groups determined by one-way ANOVA followed by Bonferroni’s post-test.