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Figure 3 | Molecular Cancer

Figure 3

From: Role of p38 and JNK MAPK signaling pathways and tumor suppressor p53 on induction of apoptosis in response to Ad-eIF5A1 in A549 lung cancer cells

Figure 3

Ad-eIF5A1 infection upregulates Bax and Bid. A549 lung carcinoma cells were infected with adenovirus expressing eIF5A1 at increasing multiplicities of infection (MOI). Adenoviral infection with Ad-eIF5A1 (5A) was at MOI’s of 5, 10, 25 or 80 while Ad-LacZ (L) was given at an MOI of 80. Forty-eight hours later, the cell lysate was harvested and used for western blot analysis of Bcl-2 family proteins. The data is representative of three independent experiments.

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Molecular Cancer

ISSN: 1476-4598