Figure 2From: Gene expression profiling of chronic myeloid leukemia with variant t(9;22) reveals a different signature from cases with classic translocationDeregulated genes in CML cases with variant t(9;22). (A) “Hematological System Development and Function, Tissue Morphology, Cellular Development” network deriving from GEP in CML cases with variant t(9;22). Both direct (solid lines) and indirect (dashed lines) interactions among genes are shown. Colored symbols correspond to genes included in our set of differentially expressed genes (red = upregulated and green = downregulated). (B) The involvement of TRIB1, PTK2B and C5AR1 kinases in the RAS/MAPK pathway downstream to the BCR/ABL oncoprotein.Back to article page